| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 22/02/25 22:45 | Los Angeles FC | Minnesota United FC | 1-0 |
| 23/02/25 01:30 | Orlando City | Philadelphia Union | 2-4 |
| 23/02/25 01:30 | D.C. United | Toronto FC | 2-2 |
| 23/02/25 01:30 | Columbus Crew | Chicago Fire | 4-2 |
| 23/02/25 01:30 | Cincinnati FC | New York Red Bulls | 1-0 |
| 23/02/25 01:30 | Atlanta United FC | CF Montreal | 3-2 |
| 23/02/25 01:30 | Inter Miami CF | New York City FC | 2-2 |
| 23/02/25 02:30 | St. Louis City SC | Colorado Rapids | 0-0 |
| 23/02/25 02:30 | Nashville SC | New England Revolution | 0-0 |
| 23/02/25 02:30 | Houston Dynamo | FC Dallas | 1-2 |
| 23/02/25 02:30 | Austin FC | Sporting Kansas City | 1-0 |
| 23/02/25 04:30 | Seattle Sounders | Charlotte FC | 2-2 |
| 23/02/25 04:30 | San Jose Earthquakes | Real Salt Lake | 4-0 |
| 23/02/25 22:00 | Portland Timbers | Vancouver Whitecaps | --- |
| 24/02/25 01:00 | Los Angeles Galaxy | San Diego FC | --- |