| Date | À domicile | A l'extérieur | Résultat |
|---|---|---|---|
| 19/04/25 19:45 | Austin FC | Los Angeles Galaxy | --- |
| 19/04/25 22:30 | Columbus Crew | Inter Miami CF | --- |
| 20/04/25 01:30 | Seattle Sounders | Nashville SC | --- |
| 20/04/25 01:30 | New York Red Bulls | D.C. United | --- |
| 20/04/25 01:30 | New England Revolution | New York City FC | --- |
| 20/04/25 01:30 | Philadelphia Union | Atlanta United FC | --- |
| 20/04/25 01:30 | CF Montreal | Orlando City | --- |
| 20/04/25 01:30 | Charlotte FC | San Diego FC | --- |
| 20/04/25 02:30 | St. Louis City SC | Vancouver Whitecaps | --- |
| 20/04/25 02:30 | Minnesota United FC | FC Dallas | --- |
| 20/04/25 02:30 | Houston Dynamo | Colorado Rapids | --- |
| 20/04/25 02:30 | Chicago Fire | Cincinnati FC | --- |
| 20/04/25 03:30 | Real Salt Lake | Toronto FC | --- |
| 20/04/25 04:15 | Portland Timbers | Los Angeles FC | --- |
| 20/04/25 04:30 | San Jose Earthquakes | Sporting Kansas City | --- |